Lei Zhang Selected Research

ubenimex

6/2013	Design, synthesis and preliminary activity evaluation of novel 3-amino-2-hydroxyl-3-phenylpropanoic acid derivatives as aminopeptidase N/CD13 inhibitors.
5/2013	Discovery of a synthetic Aminopeptidase N inhibitor LB-4b as a potential anticancer agent.
6/2012	Design, synthesis and biological evaluation of novel amino acid ureido derivatives as aminopeptidase N/CD13 inhibitors.
4/2012	Synthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors.
8/2006	Bestatin, an inhibitor of aminopeptidases, provides a chemical genetics approach to dissect jasmonate signaling in Arabidopsis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Lei Zhang Research Topics

Disease

1129	Neoplasms (Cancer) 12/2022 - 02/2002
223	Inflammation (Inflammations) 12/2022 - 10/2004
206	Infections 10/2022 - 11/2002
158	Neoplasm Metastasis (Metastasis) 12/2022 - 08/2005
135	Breast Neoplasms (Breast Cancer) 12/2022 - 12/2004
130	Hepatocellular Carcinoma (Hepatoma) 05/2022 - 06/2002
111	Carcinogenesis 06/2022 - 02/2002
90	Hypoxia (Hypoxemia) 01/2022 - 12/2004
88	Fibrosis (Cirrhosis) 10/2022 - 05/2005
86	Carcinoma (Carcinomatosis) 02/2022 - 07/2005
80	Wounds and Injuries (Trauma) 12/2022 - 04/2004
69	Colorectal Neoplasms (Colorectal Cancer) 05/2022 - 11/2011
67	Lung Neoplasms (Lung Cancer) 07/2022 - 05/2005
66	Body Weight (Weight, Body) 10/2022 - 10/2005
65	Cardiovascular Diseases (Cardiovascular Disease) 11/2022 - 06/2003
65	Obesity 10/2022 - 01/2005
64	Type 2 Diabetes Mellitus (MODY) 11/2022 - 03/2010
63	Stroke (Strokes) 12/2022 - 06/2003
60	Pain (Aches) 08/2022 - 02/2003
60	Hemorrhage 07/2022 - 11/2005
60	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2022 - 11/2008
58	Alzheimer Disease (Alzheimer's Disease) 03/2022 - 07/2009
58	Insulin Resistance 01/2022 - 09/2003
56	Glioma (Gliomas) 12/2022 - 12/2004
56	Atherosclerosis 06/2022 - 02/2006
56	Stomach Neoplasms (Stomach Cancer) 06/2022 - 11/2010
52	Myocardial Infarction 11/2021 - 03/2005
48	Leukemia 12/2022 - 09/2007
45	COVID-19 10/2022 - 01/2020
45	Hypertension (High Blood Pressure) 02/2022 - 06/2003
45	Ischemia 01/2022 - 07/2005
44	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 08/2003
43	Reperfusion Injury 01/2022 - 06/2007
40	Ischemic Stroke 11/2022 - 07/2009
40	Necrosis 01/2022 - 07/2005
38	Cognitive Dysfunction 01/2022 - 02/2010
38	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2022 - 01/2005
34	Thrombosis (Thrombus) 11/2022 - 08/2007
34	Osteoporosis 08/2022 - 08/2009
33	Rheumatoid Arthritis 06/2022 - 02/2006
33	Brain Ischemia (Cerebral Ischemia) 01/2022 - 10/2004
32	Schizophrenia (Dementia Praecox) 09/2022 - 08/2005
32	Squamous Cell Carcinoma of Head and Neck 01/2022 - 02/2005
31	Liver Cirrhosis (Hepatic Cirrhosis) 12/2022 - 01/2009
31	Aortic Dissection 07/2022 - 07/2011
31	Adenocarcinoma of Lung 04/2022 - 11/2015
31	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 03/2009
30	Infarction (Infarctions) 01/2022 - 10/2005
30	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 07/2010
30	Lymphatic Metastasis 01/2021 - 02/2005
29	Renal Cell Carcinoma (Grawitz Tumor) 05/2022 - 03/2003
28	Osteoarthritis 07/2022 - 06/2008
28	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 05/2011
28	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 12/2003

Drug/Important Bio-Agent (IBA)

370	Proteins (Proteins, Gene)FDA Link 12/2022 - 01/2003
268	Biomarkers (Surrogate Marker)IBA 10/2022 - 11/2007
209	Pharmaceutical PreparationsIBA 07/2022 - 01/2005
159	MicroRNAs (MicroRNA)IBA 05/2022 - 05/2012
132	Biological ProductsIBA 05/2022 - 03/2003
123	CytokinesIBA 10/2022 - 11/2002
121	Messenger RNA (mRNA)IBA 06/2022 - 03/2002
97	Glucose (Dextrose)FDA LinkGeneric 09/2022 - 09/2003
95	RNA (Ribonucleic Acid)IBA 05/2022 - 12/2004
93	Long Noncoding RNAIBA 09/2022 - 01/2014
69	EnzymesIBA 01/2022 - 10/2003
63	Therapeutic UsesIBA 11/2022 - 06/2004
62	DNA (Deoxyribonucleic Acid)IBA 12/2022 - 08/2002
56	Transcription Factors (Transcription Factor)IBA 12/2022 - 12/2003
52	LipidsIBA 05/2022 - 09/2007
51	Phosphotransferases (Kinase)IBA 05/2022 - 02/2003
48	Peptides (Polypeptides)IBA 04/2022 - 06/2004
48	Insulin (Novolin)FDA Link 02/2022 - 09/2003
48	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 01/2005
47	AntigensIBA 01/2022 - 12/2003
46	Small Interfering RNA (siRNA)IBA 10/2022 - 01/2008
45	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022 - 09/2003
45	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2021 - 12/2003
44	VaccinesIBA 01/2022 - 12/2004
41	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2022 - 06/2007
41	Indicators and Reagents (Reagents)IBA 07/2022 - 09/2006
38	Inosine Triphosphate (ITP)IBA 01/2022 - 01/2005
37	LigandsIBA 03/2022 - 12/2004
36	Circular RNAIBA 10/2022 - 04/2017
36	Interleukin-6 (Interleukin 6)IBA 10/2022 - 02/2005
34	AcidsIBA 01/2022 - 01/2007
33	Blood Glucose (Blood Sugar)IBA 01/2022 - 07/2010
32	Anti-Bacterial Agents (Antibiotics)IBA 12/2022 - 07/2009
31	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 01/2009
30	LipopolysaccharidesIBA 10/2022 - 10/2006
29	AntibodiesIBA 12/2022 - 08/2006
28	CholesterolIBA 06/2022 - 06/2003
28	Oxygen (Dioxygen)IBA 01/2022 - 06/2006

Therapy/Procedure

474	Therapeutics 12/2022 - 07/2003
139	Drug Therapy (Chemotherapy) 12/2022 - 12/2005
65	Transplantation 06/2022 - 02/2002
60	Immunotherapy 12/2022 - 12/2007
51	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 07/2009
50	Radiotherapy 09/2022 - 12/2005
40	Stents 02/2022 - 12/2007
33	Aftercare (After-Treatment) 07/2022 - 09/2008